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TRP 3.15 Parasitair: Schistosomiasis (S. mansoni, S. haematobium, S. intercalatum, S. japonicum, S. mekongi)

Advices

≥ 18 years

Indications: Katayama-syndroom

Priority Medication Remarks
Medication:

praziquantel po 40mg/kg 1dd 3 days

Remarks:

Zo nodig ook corticosteroïden gedurende 3 dagen

Praziquantel herhalen na 3 maanden

≥ 18 years

Indications: S. mansoni, S. haematobium, S. intercalatum

Priority Medication Remarks
Medication:

praziquantel po 40mg/kg one-off

Remarks:

Herhalen na 4 weken

≥ 18 years

Indications: S. japonicum, S. mekongi

Priority Medication Remarks
Medication:

praziquantel po 30mg/kg 2dd 1 days

Remarks:

Herhalen na 4 weken

≥ 18 years

Indications: CZS lokalisatie

Priority Medication Remarks
Medication:

praziquantel po 30mg/kg 2dd 3 days

Remarks:

Herhalen na 4 weken

General comments

Katayama-syndroom; praziquantel is niet effectief tegen jonge parasitaire stadia (schistosomula). Daarom altijd praziquantel behandeling herhalen eenmalig na 3-6 maanden.

Therapiefalen na eenmalige dosering praziquantel komt frequent (20-30%) voor. Herhalen behandeling na 4 weken.

CZS localisatie praziquantel met hoge dosis corticosteroïden (prednison 60 mg/dag) gedurende 28 dagen.

Sources

  1. Behandeling Importziekten, P.A. Kager (ed), AMC, Amsterdam, 2004; update 2013

  2. Transactions of the Royal Society of Tropical Medicine and Hygiene (2008) 102, 107—116

  3. Revista da Sociedade Brasileira de Medicina Tropical 40(5):574-581, set-out, 2007 Ross AG

  4. McManus DP, Farrar J, Hunstman RJ, Gray DJ, Li YS. Neuroschistosomiasis. J Neurol. 2012;259:22–32

  5. J Travel Med. 2010 Mar-Apr;17(2):94-9. Helleberg M, Thybo S. High rate of failure in treatment of imported schistosomiasis.

  6. Ferrari TC, Moreira PR. Neuroschistosomiasis: clinical symptoms and pathogenesis. Lancet Neurol. 2011;10(9):853-64

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-351673.1
Updated: 10/11/2016 - 00:20
Status: Published